Paraxanthine
Product Specifications
CAS Number
611-59-6
Target
Endogenous Metabolite, Drug Metabolite
Related Pathways
Metabolism
Purity
0.9999
Bioactivity
Paraxanthine (1,7-dimethylxanthine) is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Paraxanthine is structurally similar to caffeine and possibly mediates the physiological effects of caffeine. Also Paraxanthine acts as a competitive phosphodiesterase inhibitor, which increases intracellular cAMP, activates PKA, inhibits TNF-α and leukotriene synthesis. In addition, Paraxanthine acts as a Na+/K+ ATPase enzymatic effector.
Smiles
Cn1cnc2[nH]c(=O)n(C)c(=O)c12
Molecular Formula
C7H8N4O2
Molecular Weight
180.16
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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