PS47

PS47 is an inactive E-isomer of PS48. PS48 is an activator of PDK1. PS47 can be used as a negative control for PS48[1][2].

Product Specifications

CAS Number

[1180676-33-8]

UNSPSC

12352005

Target

PDK-1

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ps47.html

Concentration

10mM

Purity

98.83

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(O)/C=C(C1=CC=CC=C1)\CCC2=CC=C(Cl)C=C2

Molecular Formula

C17H15ClO2

Molecular Weight

286.75

References & Citations

[1]Hindie V, et, al. Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1. Nat Chem Biol. 2009 Oct;5 (10) :758-64.|[2]Pastor-Flores D, et, al. PIF-pocket as a target for C. albicans Pkh selective inhibitors. ACS Chem Biol. 2013 Oct 18;8 (10) :2283-92.