PS47
PS47 is an inactive E-isomer of PS48. PS48 is an activator of PDK1. PS47 can be used as a negative control for PS48[1][2].
Product Specifications
CAS Number
[1180676-33-8]
UNSPSC
12352005
Target
PDK-1
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ps47.html
Concentration
10mM
Purity
98.83
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)/C=C(C1=CC=CC=C1)\CCC2=CC=C(Cl)C=C2
Molecular Formula
C17H15ClO2
Molecular Weight
286.75
References & Citations
[1]Hindie V, et, al. Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1. Nat Chem Biol. 2009 Oct;5 (10) :758-64.|[2]Pastor-Flores D, et, al. PIF-pocket as a target for C. albicans Pkh selective inhibitors. ACS Chem Biol. 2013 Oct 18;8 (10) :2283-92.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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