BMS202 hydrochloride (1675203-84-5 (free base) )
Product Specifications
CAS Number
2089334-95-0
Target
Apoptosis, PD-1/PD-L1
Related Pathways
Cell Cycle/Checkpoint, Apoptosis, Immunology/Inflammation
Purity
0.9947
Bioactivity
BMS202 hydrochloride (1675203-84-5 (free base) ) (PD-1/PD-L1 inhibitor 2 hydrochloride) is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM) . Biophysical studies demonstrate that BMS202 binds directly to PD-L1. Binding of BMS202 promotes PD-L1 dimerisation and blocks the PD-L1/ PD1 interaction.
Smiles
Cl.COc1nc(OCc2cccc(c2C)-c2ccccc2)ccc1CNCCNC(C)=O
Molecular Formula
C25H30ClN3O3
Molecular Weight
455.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC042001-100 1x 100 µL
IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) (1B1.3a), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC472075-100 1x 100 µL
MyoD1 (Rhabdomyosarcoma Marker) (MYOD1/2075R), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details