HC067047 Hydrochloride (883031-03-6 free base)
Product Specifications
CAS Number
1481646-76-7
Target
TRP/TRPV Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9995
Bioactivity
HC-067047 hydrochloride is a potent and selective TRPV4 antagonist, effectively and reversibly inhibiting currents through human, rat, and mouse TRPV4 orthologs with IC50 values of 486 nM, 133 nM, and 17 nM, respectively.
Smiles
O=C(C1=C(C)N(CCCN2CCOCC2)C(C3=CC=CC=C3)=C1)NC4=CC=CC(C(F)(F)F)=C4.[H]Cl
Molecular Formula
C26H29ClF3N3O2
Molecular Weight
507.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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