What is the catalog number for SB297006?

The catalog number for SB297006 is T4674.

What sizes are available for SB297006?

SB297006 is available in the following size(s): 5 mg, 1 mL - 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg, 200 mg.

How many pack sizes does SB297006 come in?

SB297006 is available in 7 different pack sizes.

Is SB297006 in stock?

SB297006 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SB297006?

SB297006 is manufactured by Molfinity.

What is the estimated delivery time for SB297006?

Estimated delivery time for SB297006 is approximately 10 business day(s), depending on your location.

SB297006

Product Specifications

CAS Number

58816-69-6

Target

CCR

Related Pathways

Immunology/Inflammation, GPCR/G Protein, Microbiology/Virology

Purity

0.9965

Bioactivity

SB297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 250-fold selective for CCR3 over a panel of other chemokine receptors. SB 297006 blocks CCR3-mediated calcium mobilization induced by eotaxin, eotaxin-2, and MCP-4 in transfected cells. It suppresses antigen-induced accumulation of Th2 lymphocytes and eosinophils in lungs of mice when delivered subcutaneously (100 mg/kg) .