TCJL37
Product Specifications
CAS Number
1258294-34-6
Target
Others, JAK
Related Pathways
Angiogenesis, Others, Stem Cells, JAK/STAT signaling, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors
Bioactivity
TCJL37, a potent, selective, and orally bioavailable inhibitor of TYK2, exhibits a K i value of 1.6 nM. It is useful for researching inflammatory bowel diseases (IBD) [1].
Smiles
N(C(=O)C1=C(Cl)C=C(C#N)C=C1F)C=2C=C(NC(=O)[C@@H]3[C@H](F)C3)N=CC2
Molecular Formula
C17H11ClF2N4O2
Molecular Weight
376.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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