ML 297
Product Specifications
CAS Number
1443246-62-5
Target
Potassium Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9785
Bioactivity
ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively) . ML 297 exhibits no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels, and has minimal effect on a panel of other ion channels, receptors and transporters.
Smiles
Cc1cc(NC(=O)Nc2ccc(F)c(F)c2)n(n1)-c1ccccc1
Molecular Formula
C17H14F2N4O
Molecular Weight
328.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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