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ML 297

Product Specifications

CAS Number

1443246-62-5

Target

Potassium Channel

Related Pathways

Membrane transporter/Ion channel

Purity

0.9785

Bioactivity

ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively) . ML 297 exhibits no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels, and has minimal effect on a panel of other ion channels, receptors and transporters.

Smiles

Cc1cc(NC(=O)Nc2ccc(F)c(F)c2)n(n1)-c1ccccc1

Molecular Formula

C17H14F2N4O

Molecular Weight

328.32

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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