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M2I-1

Product Specifications

CAS Number

312271-03-7

Target

Others, Chk

Related Pathways

Others, Cell Cycle/Checkpoint

Purity

>99.99%

Bioactivity

M2I-1 a small Mad2 inhibitor-1. the first small molecule inhibitor targeting the binding of Mad2 to Cdc20, an essential proteinprotein interaction (PPI) within the SAC. It can disturbs conformational dynamics of Mad2 critical for complex formation with Cdc20. It can also inhibited the Mad2-F-Mbp1 interaction in FP assays.

Smiles

CC(C)CN(CC(C)C)c1ccc(C=C2C(=O)NC(=S)NC2=O)cc1[N+]([O-])=O

Molecular Formula

C19H24N4O4S

Molecular Weight

404.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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