M2I-1
Product Specifications
CAS Number
312271-03-7
Target
Others, Chk
Related Pathways
Others, Cell Cycle/Checkpoint
Purity
>99.99%
Bioactivity
M2I-1 a small Mad2 inhibitor-1. the first small molecule inhibitor targeting the binding of Mad2 to Cdc20, an essential proteinprotein interaction (PPI) within the SAC. It can disturbs conformational dynamics of Mad2 critical for complex formation with Cdc20. It can also inhibited the Mad2-F-Mbp1 interaction in FP assays.
Smiles
CC(C)CN(CC(C)C)c1ccc(C=C2C(=O)NC(=S)NC2=O)cc1[N+]([O-])=O
Molecular Formula
C19H24N4O4S
Molecular Weight
404.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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