BGG463
Product Specifications
CAS Number
890129-26-7
Target
CDK, Bcr-Abl
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, Cell Cycle/Checkpoint, Cytoskeletal Signaling
Purity
>99.99%
Bioactivity
BGG463 (K 0859) can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with a 50% inhibitory concentration (IC50) of 0.25 μM, 0.09 μM and 0.590 μM, respectively.
Smiles
CN1CCN(Cc2ccc(NC(=O)c3cccc4cc(Oc5cc(NC(C)=O)ncn5)ccc34)cc2C(F)(F)F)CC1
Molecular Formula
C30H29F3N6O3
Molecular Weight
578.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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