YHO-13177
Product Specifications
CAS Number
912287-56-0
Target
BCRP
Related Pathways
Membrane transporter/Ion channel
Purity
0.9878
Bioactivity
YHO-13177 is a potent and specific inhibitor of BCRP, which enhances the cytotoxicity of SN-38 in cancer cells without affecting P-glycoprotein–mediated paclitaxel resistance in [MDR1]-transduced human leukemia [K562] cells.
Smiles
COc1ccc(cc1OC)C(=C\c1ccc(s1)N1CCC(O)CC1)\C#N
Molecular Formula
C20H22N2O3S
Molecular Weight
370.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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