YHO-13177

Product Specifications

CAS Number

912287-56-0

Target

BCRP

Related Pathways

Membrane transporter/Ion channel

Purity

0.9878

Bioactivity

YHO-13177 is a potent and specific inhibitor of BCRP, which enhances the cytotoxicity of SN-38 in cancer cells without affecting P-glycoprotein–mediated paclitaxel resistance in [MDR1]-transduced human leukemia [K562] cells.

Smiles

COc1ccc(cc1OC)C(=C\c1ccc(s1)N1CCC(O)CC1)\C#N

Molecular Formula

C20H22N2O3S

Molecular Weight

370.47

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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