Linrodostat mesylate
Product Specifications
CAS Number
2221034-29-1
Target
Others, IDO, Indoleamine 2,3-Dioxygenase (IDO)
Related Pathways
Others, Metabolism
Bioactivity
Linrodostat (BMS-986205, ONO-7701, and F001287) is a selective and orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities. By inhibiting IDO1 and reducing kynurenine in tumor cells, BMS-986205 restores and promotes the proliferation and activation of various immune cells and causes a reduction in tumor-associated regulatory T cells (Tregs) .
Smiles
S(C)(=O)(=O)O.FC1=CC=2C(=CC=NC2C=C1)[C@@H]3CC[C@]([C@H](C(NC4=CC=C(Cl)C=C4)=O)C)(CC3)[H]
Molecular Formula
C25H28ClFN2O4S
Molecular Weight
507.02
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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