Licochalcone D

Product Specifications

CAS Number

144506-15-0

Target

NF-κB, Apoptosis, Reactive Oxygen Species, ERK, ROS

Related Pathways

Metabolism, Apoptosis, Immunology/Inflammation, NF-κB, MAPK

Purity

0.999

Bioactivity

Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotective potential against myocardial ischemia/reperfusion injury in langendorff-perfused rat hearts. Licochalcone D has anti-inflammatory activity, it shows suppression ability of nitric oxide (NO) production. Licochalcone D has anti-allergic activity, it suppresses degranulation by decreasing the intracellular Ca2+ level and tyrosine phosphorylation of ERK in RBL-2H3 cells.