Licochalcone D
Product Specifications
CAS Number
144506-15-0
Target
NF-?B|||Apoptosis|||Reactive Oxygen Species|||ERK|||ROS
Related Pathways
Metabolism|||Apoptosis|||Immunology/Inflammation|||NF-?B|||MAPK
Purity
0.999
Bioactivity
Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotective potential against myocardial ischemia/reperfusion injury in langendorff-perfused rat hearts. Licochalcone D has anti-inflammatory activity, it shows suppression ability of nitric oxide (NO) production. Licochalcone D has anti-allergic activity, it suppresses degranulation by decreasing the intracellular Ca2+ level and tyrosine phosphorylation of ERK in RBL-2H3 cells.
Smiles
COc1c(O)c(O)ccc1\C=C\C(=O)c1ccc(O)c(CC=C(C)C)c1
Molecular Formula
C21H22O5
Molecular Weight
354.4
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/8FC950FC-BFAF-4BBC-9FF1-7FBC014D1236/T4518
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6352066-01 0.1 mL
STK32A, NT (STK32A, Serine/threonine-protein kinase 32A, YANK1) (MaxLight 490)
Ask
View Details