GSK-25
Product Specifications
CAS Number
874119-56-9
Target
MTOR, ROCK, S6 Kinase
Related Pathways
Stem Cells, Cell Cycle/Checkpoint, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, MAPK
Purity
0.9914
Bioactivity
GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested) .
Smiles
CC1=C(C(N=C(N1)c1ccnc(Cl)c1)c1ccc(Cl)cc1F)C(=O)Nc1cc2cn[nH]c2cc1F
Molecular Formula
C24H16Cl2F2N6O
Molecular Weight
513.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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