Lazertinib
Product Specifications
CAS Number
1903008-80-9
Target
EGFR
Related Pathways
Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Purity
0.9996
Bioactivity
Lazertinib (GNS-1480) is an effective, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T790M, Del19, L85R and Wild type EGFR respectively.
Smiles
COc1cc(N2CCOCC2)c(NC(=O)C=C)cc1Nc1nccc(n1)-n1cc(CN(C)C)c(n1)-c1ccccc1
Molecular Formula
C30H34N8O3
Molecular Weight
554.64
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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