Lazertinib

Product Specifications

CAS Number

1903008-80-9

Target

EGFR

Related Pathways

Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

Purity

0.9996

Bioactivity

Lazertinib (GNS-1480) is an effective, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T790M, Del19, L85R and Wild type EGFR respectively.

Smiles

COc1cc(N2CCOCC2)c(NC(=O)C=C)cc1Nc1nccc(n1)-n1cc(CN(C)C)c(n1)-c1ccccc1

Molecular Formula

C30H34N8O3

Molecular Weight

554.64

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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