Tucidinostat
Product Specifications
CAS Number
1616493-44-7
Target
HDAC
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair
Purity
0.9995
Bioactivity
Tucidinostat (Chidamide) is an effective and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8/11 (IC50: 733/432 nM), and shows no effect on HDAC4/5/6/7/9.
Smiles
Nc1cc(F)ccc1NC(=O)c1ccc(CNC(=O)\C=C\c2cccnc2)cc1
Molecular Formula
C22H19FN4O2
Molecular Weight
390.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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