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Tucidinostat

Product Specifications

CAS Number

1616493-44-7

Target

HDAC

Related Pathways

Chromatin/Epigenetic, DNA Damage/DNA Repair

Purity

0.9995

Bioactivity

Tucidinostat (Chidamide) is an effective and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8/11 (IC50: 733/432 nM), and shows no effect on HDAC4/5/6/7/9.

Smiles

Nc1cc(F)ccc1NC(=O)c1ccc(CNC(=O)\C=C\c2cccnc2)cc1

Molecular Formula

C22H19FN4O2

Molecular Weight

390.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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