Rucaparib
Product Specifications
CAS Number
283173-50-2
Target
PARP
Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic
Purity
0.9989
Bioactivity
Rucaparib (PF-01367338) is a PARP protein inhibitor (PARP-1 Ki=1.4 nM) and hexose hexose-6-phosphate dehydrogenase (H6PD) inhibitor with oral activity. Rucaparib exhibits antitumor activity, with activity against desmoplasia-resistant prostate cancer (CRPC) .
Smiles
O=C1C2=C3C(=C(NC3=CC(F)=C2)C4=CC=C(CNC)C=C4)CCN1
Molecular Formula
C19H18FN3O
Molecular Weight
323.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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