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Rucaparib

Product Specifications

CAS Number

283173-50-2

Target

PARP

Related Pathways

DNA Damage/DNA Repair, Chromatin/Epigenetic

Purity

0.9989

Bioactivity

Rucaparib (PF-01367338) is a PARP protein inhibitor (PARP-1 Ki=1.4 nM) and hexose hexose-6-phosphate dehydrogenase (H6PD) inhibitor with oral activity. Rucaparib exhibits antitumor activity, with activity against desmoplasia-resistant prostate cancer (CRPC) .

Smiles

O=C1C2=C3C(=C(NC3=CC(F)=C2)C4=CC=C(CNC)C=C4)CCN1

Molecular Formula

C19H18FN3O

Molecular Weight

323.36

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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