AZ32
Product Specifications
CAS Number
2288709-96-4
Target
ATM/ATR
Related Pathways
DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling
Purity
0.9994
Bioactivity
AZ32 is an orally bioavailable, blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for the ATM enzyme and an IC50 of 0.31 μM for ATM in cells.
Smiles
CNC(=O)c1ccc(cc1)-c1cnc2cnc(cn12)-c1ccccc1
Molecular Formula
C20H16N4O
Molecular Weight
328.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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