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AZ32

Product Specifications

CAS Number

2288709-96-4

Target

ATM/ATR

Related Pathways

DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling

Purity

0.9994

Bioactivity

AZ32 is an orally bioavailable, blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for the ATM enzyme and an IC50 of 0.31 μM for ATM in cells.

Smiles

CNC(=O)c1ccc(cc1)-c1cnc2cnc(cn12)-c1ccccc1

Molecular Formula

C20H16N4O

Molecular Weight

328.37

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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