Tirapazamine
Product Specifications
CAS Number
27314-97-2
Target
Others, DNA/RNA Synthesis
Related Pathways
Others, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Purity
0.9987
Bioactivity
Tirapazamine (Win59075) is a potent cytotoxic agent under hypoxic conditions, can induce apoptosis by inducing breaks in single and double-stranded DNA, as well as chromosomal breaks. The compound sensitizes cells to other ionizing radiation and other cytotoxic agents like cisplatin.
Smiles
On1c2ccccc2[n+]([O-])nc1=N
Molecular Formula
C7H6N4O2
Molecular Weight
178.15
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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