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CCT241736

Product Specifications

CAS Number

1402709-93-6

Target

FLT, Aurora Kinase

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis, Cell Cycle/Checkpoint, Chromatin/Epigenetic

Purity

0.9988

Bioactivity

CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3, CCT241736, an advanced analog of CCT137690, is a preclinical development candidate for the treatment of human malignancies, and in particular AML in adults and children.

Smiles

Cc1nn(C)cc1-c1nc2c(N3CCN(Cc4ccc(Cl)cc4)CC3)c(Cl)cnc2[nH]1

Molecular Formula

C22H23Cl2N7

Molecular Weight

456.37

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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