JK-P3
Product Specifications
CAS Number
942655-44-9
Target
FGFR|||VEGFR
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis
Purity
>99.99%
Bioactivity
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 ?M) . JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation.
Smiles
COc1ccc(cc1OC)C(=O)Nc1cc([nH]n1)-c1ccccc1
Molecular Formula
C18H17N3O3
Molecular Weight
323.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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