LM10
Product Specifications
CAS Number
1316695-35-8
Target
Others, IDO, Indoleamine 2,3-Dioxygenase (IDO)
Related Pathways
Others, Metabolism
Purity
0.9994
Bioactivity
Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively) . Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. Reduces growth of TDO-expressing P815 mastocytoma tumors in mice. Orally bioavailable.
Smiles
Fc1ccc2c(\C=C\c3nnn[nH]3)c[nH]c2c1
Molecular Formula
C11H8FN5
Molecular Weight
229.21
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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