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LM10

Product Specifications

CAS Number

1316695-35-8

Target

Others, IDO, Indoleamine 2,3-Dioxygenase (IDO)

Related Pathways

Others, Metabolism

Purity

0.9994

Bioactivity

Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively) . Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. Reduces growth of TDO-expressing P815 mastocytoma tumors in mice. Orally bioavailable.

Smiles

Fc1ccc2c(\C=C\c3nnn[nH]3)c[nH]c2c1

Molecular Formula

C11H8FN5

Molecular Weight

229.21

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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