Gilteritinib
Product Specifications
CAS Number
1254053-43-4
Target
C-Kit, FLT, TAM Receptor
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Purity
0.999
Bioactivity
Gilteritinib (ASP2215) is a potent inhibitor of FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM, respectively) . In preclinical studies, gilteritinib demonstrated strong antileukemic and antitumor effects. Gilteritinib is currently in several Phase 3 clinical trials for acute myeloid leukemia.
Smiles
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)nc1NC1CCOCC1
Molecular Formula
C29H44N8O3
Molecular Weight
552.71
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNUB3065-500 1x 500 µL
PCNA (Proliferating Cell Nuclear Antigen) (G1- & S-phase Marker) (PC5), 0.2mg/mL
Sign In for Pricing
View Details 
BNC043540-100 1x 100 µL
CD31 / PECAM-1 (Endothelial Cell Marker) (PECAM1/3540), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
PKSH033962-01 20 µg
Recombinant Human CD47/IAP/OA3 (C-Avi-6His) Biotinylated
Sign In for Pricing
View Details