Gilteritinib
Product Specifications
CAS Number
1254053-43-4
Target
C-Kit|||FLT|||TAM Receptor
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis
Purity
0.999
Bioactivity
Gilteritinib (ASP2215) is a potent inhibitor of FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM, respectively) . In preclinical studies, gilteritinib demonstrated strong antileukemic and antitumor effects. Gilteritinib is currently in several Phase 3 clinical trials for acute myeloid leukemia.
Smiles
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)nc1NC1CCOCC1
Molecular Formula
C29H44N8O3
Molecular Weight
552.71
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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