Gilteritinib
Product Specifications
CAS Number
1254053-43-4
Target
C-Kit, FLT, TAM Receptor
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Purity
0.999
Bioactivity
Gilteritinib (ASP2215) is a potent inhibitor of FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM, respectively) . In preclinical studies, gilteritinib demonstrated strong antileukemic and antitumor effects. Gilteritinib is currently in several Phase 3 clinical trials for acute myeloid leukemia.
Smiles
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)nc1NC1CCOCC1
Molecular Formula
C29H44N8O3
Molecular Weight
552.71
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS7263151-01 48 Well
Monkey Secreted Phosphoprotein 24 (SPP2) ELISA Kit
Sign In for Pricing
View Details 
MBS7263151-02 96 Well
Monkey Secreted Phosphoprotein 24 (SPP2) ELISA Kit
Sign In for Pricing
View Details MBS7263151-03 5x 96 Well
Monkey Secreted Phosphoprotein 24 (SPP2) ELISA Kit
Sign In for Pricing
View Details MBS7263151-04 10x 96 Well
Monkey Secreted Phosphoprotein 24 (SPP2) ELISA Kit
Sign In for Pricing
View Details MBS1371767-01 0.02 mg (E-Coli)
Recombinant Xanthomonas oryzae pv. oryzae Elongation factor P-like protein (XOO2755)
Sign In for Pricing
View Details 
MBS1371767-02 0.1 mg (E-Coli)
Recombinant Xanthomonas oryzae pv. oryzae Elongation factor P-like protein (XOO2755)
Sign In for Pricing
View Details