LX2343

Product Specifications

CAS Number

333745-53-2

Target

Beta-Secretase, Beta Amyloid, BACE, Autophagy, PI3K

Related Pathways

Neuroscience, Autophagy, PI3K/Akt/mTOR signaling

Purity

0.9992

Bioactivity

LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM and acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23 μM. Additionally, LX2343 stimulates autophagy, promoting Aβ clearance.

Smiles

COc1ccc(Cl)cc1N(CC(=O)Nc1ccc2OCOc2c1)S(=O)(=O)c1ccccc1

Molecular Formula

C22H19ClN2O6S

Molecular Weight

474.91

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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