LX2343
Product Specifications
CAS Number
333745-53-2
Target
Beta-Secretase|||Beta Amyloid|||BACE|||Autophagy|||PI3K
Related Pathways
Neuroscience|||Autophagy|||PI3K/Akt/mTOR signaling
Purity
0.9992
Bioactivity
LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 ?M and acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23 ?M. Additionally, LX2343 stimulates autophagy, promoting A? clearance.
Smiles
COc1ccc(Cl)cc1N(CC(=O)Nc1ccc2OCOc2c1)S(=O)(=O)c1ccccc1
Molecular Formula
C22H19ClN2O6S
Molecular Weight
474.91
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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