KPT9274
Product Specifications
CAS Number
1643913-93-2
Target
NAMPT|||PAK
Related Pathways
Cytoskeletal Signaling|||Metabolism
Purity
0.9993
Bioactivity
KPT9274 (PAK4-IN-1) is a non-competitive dual inhibitor of PAK4 and NAMPT (IC50= ~120 nM) . It is an orally bioavailable small molecule.
Smiles
Nc1ccc(\C=C\C(=O)NCc2cc3cc(cc(-c4ccc(F)cc4)c3o2)-c2ccc(cc2)C(=O)N2CCC(F)(F)CC2)cn1
Molecular Formula
C35H29F3N4O3
Molecular Weight
610.62
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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