KPT9274

Product Specifications

CAS Number

1643913-93-2

Target

NAMPT|||PAK

Related Pathways

Cytoskeletal Signaling|||Metabolism

Purity

0.9993

Bioactivity

KPT9274 (PAK4-IN-1) is a non-competitive dual inhibitor of PAK4 and NAMPT (IC50= ~120 nM) . It is an orally bioavailable small molecule.

Smiles

Nc1ccc(\C=C\C(=O)NCc2cc3cc(cc(-c4ccc(F)cc4)c3o2)-c2ccc(cc2)C(=O)N2CCC(F)(F)CC2)cn1

Molecular Formula

C35H29F3N4O3

Molecular Weight

610.62

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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