Prexasertib dihydrochloride

Product Specifications

CAS Number

1234015-54-3

Target

Chk|||Apoptosis|||S6 Kinase

Related Pathways

MAPK|||Apoptosis|||Cell Cycle/Checkpoint|||PI3K/Akt/mTOR signaling

Purity

0.9982

Bioactivity

Prexasertib dihydrochloride (LY2606368) is an ATP-competitive CHK1 inhibitor (Ki: 0.9 nmol/L) . in the cell-free assay, its IC50 values are 8 nM and 9 nM for CHK2 and RSK, respectively.

Smiles

Cl.Cl.COc1cccc(OCCCN)c1-c1cc(Nc2cnc(cn2)C#N)n[nH]1

Molecular Formula

C18H21Cl2N7O2

Molecular Weight

438.31

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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