Prexasertib dihydrochloride
Product Specifications
CAS Number
1234015-54-3
Target
Chk, Apoptosis, S6 Kinase
Related Pathways
MAPK, Apoptosis, Cell Cycle/Checkpoint, PI3K/Akt/mTOR signaling
Purity
0.9982
Bioactivity
Prexasertib dihydrochloride (LY2606368) is an ATP-competitive CHK1 inhibitor (Ki: 0.9 nmol/L) . in the cell-free assay, its IC50 values are 8 nM and 9 nM for CHK2 and RSK, respectively.
Smiles
Cl.Cl.COc1cccc(OCCCN)c1-c1cc(Nc2cnc(cn2)C#N)n[nH]1
Molecular Formula
C18H21Cl2N7O2
Molecular Weight
438.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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