Indisulam
Product Specifications
CAS Number
165668-41-7
Target
Carbonic Anhydrase, Molecular Glues, CDK
Related Pathways
Cell Cycle/Checkpoint, PROTAC, Metabolism
Purity
0.9977
Bioactivity
Indisulam (E 7070) is a carbonic anhydrase inhibitor and antitumor CDK inhibitor that targets the G1 phase of the cell cycle by depleting cyclin E, inducing p53 and p21, and inhibiting CDK2, thereby causing a blockade in the G1/S transition.
Smiles
NS(=O)(=O)c1ccc(cc1)S(=O)(=O)Nc1cccc2c(Cl)c[nH]c12
Molecular Formula
C14H12ClN3O4S2
Molecular Weight
385.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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