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Indisulam

Product Specifications

CAS Number

165668-41-7

Target

Carbonic Anhydrase, Molecular Glues, CDK

Related Pathways

Cell Cycle/Checkpoint, PROTAC, Metabolism

Purity

0.9977

Bioactivity

Indisulam (E 7070) is a carbonic anhydrase inhibitor and antitumor CDK inhibitor that targets the G1 phase of the cell cycle by depleting cyclin E, inducing p53 and p21, and inhibiting CDK2, thereby causing a blockade in the G1/S transition.

Smiles

NS(=O)(=O)c1ccc(cc1)S(=O)(=O)Nc1cccc2c(Cl)c[nH]c12

Molecular Formula

C14H12ClN3O4S2

Molecular Weight

385.85

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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