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PF 429242

Product Specifications

CAS Number

947303-87-9

Target

Fatty Acid Synthase, Lipid, Virus Protease, NPC1L1

Related Pathways

Microbiology/Virology, Metabolism, Membrane transporter/Ion channel

Purity

0.9927

Bioactivity

PF-429242 is a competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM) . It is selective for site 1 protease against a panel of serine proteases. PF-429242 inhibits rate of cholesterol synthesis in CHO cells (IC50 = 0.53 μM) .

Smiles

N(C(=O)C1=CC=C(CN(CC)CC)C=C1)(CCC2=C(OC)C=CC=C2)[C@@H]3CCNC3

Molecular Formula

C25H35N3O2

Molecular Weight

409.56

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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