Ki20227
Product Specifications
CAS Number
623142-96-1
Target
C-Kit, PDGFR, VEGFR, c-Fms, CSF-1R
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Purity
0.9988
Bioactivity
Ki-20227 is a specific c-Fms tyrosine kinase (CSF1R) inhibitor (IC50: 2 nM) . It also has certain inhibitory against VEGFR2 (IC50: 12 nM) and c-Kit/PDGFRβ (IC50: 451/217 nM), respectively.
Smiles
COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1NC(=O)NC(C)c1nccs1
Molecular Formula
C24H24N4O5S
Molecular Weight
480.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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