Ki20227

Product Specifications

CAS Number

623142-96-1

Target

C-Kit, PDGFR, VEGFR, c-Fms, CSF-1R

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis

Purity

0.9988

Bioactivity

Ki-20227 is a specific c-Fms tyrosine kinase (CSF1R) inhibitor (IC50: 2 nM) . It also has certain inhibitory against VEGFR2 (IC50: 12 nM) and c-Kit/PDGFRβ (IC50: 451/217 nM), respectively.

Smiles

COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1NC(=O)NC(C)c1nccs1

Molecular Formula

C24H24N4O5S

Molecular Weight

480.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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