Osilodrostat
Product Specifications
CAS Number
928134-65-0
Target
Glucocorticoid Receptor, Hydroxylase
Related Pathways
Metabolism, Endocrinology/Hormones
Purity
0.9936
Bioactivity
Osilodrostat (LCI699) is a potent inhibitor of human 11β-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) with IC50 values of 2.5 and 0.7 nM, respectively, and has been approved by the FDA for the treatment of Cushing's disease.
Smiles
Fc1cc(ccc1[C@H]1CCc2cncn12)C#N
Molecular Formula
C13H10FN3
Molecular Weight
227.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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