Belizatinib

1357920-84-3

ALK, Trk receptor

Angiogenesis, Tyrosine Kinase/Adaptors

0.9948

Belizatinib (TSR-011) is an effective, oral and dual inhibitor of ALK (IC50: 0.7 nM, wild-type recombinant ALK) and TRKA, TRKB, and TRKC.

CC(C)NC(=O)[C@H]1CC[C@H](CC1)n1c(NC(=O)c2ccc(F)cc2)nc2ccc(CN3CCC(CC3)C(C)(C)O)cc12

C33H44FN5O3

577.73

Ice Packs

-20°C