Roblitinib
Product Specifications
CAS Number
1708971-55-4
Target
FGFR
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis
Purity
0.99
Bioactivity
Roblitinib (FGF-401) is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4) with potential antineoplastic activity. Upon administration, Roblitinib binds to and inhibits FGFR4, leading to the inhibition of tumor cell proliferation in FGFR4-overexpressing cells. It is a receptor tyrosine kinase upregulated in certain tumor cells and involved in proliferation, differentiation, angiogenesis, and survival.
Smiles
COCCNc1cc(NC(=O)N2CCCc3cc(CN4CCN(C)CC4=O)c(C=O)nc23)ncc1C#N
Molecular Formula
C25H30N8O4
Molecular Weight
506.56
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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