PF-3758309 hydrochloride
Product Specifications
CAS Number
1279034-84-2
Target
Apoptosis|||PAK
Related Pathways
Cytoskeletal Signaling|||Apoptosis
Purity
>99.99%
Bioactivity
PF-3758309 hydrochloride (PF-03758309 hydrochloride), is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PF-3758309 hydrochloride binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serine/threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation, and survival.
Smiles
Cl.CN(C)C[C@@H](NC(=O)N1Cc2c(Nc3nc(C)nc4ccsc34)n[nH]c2C1(C)C)c1ccccc1
Molecular Formula
C25H31ClN8OS
Molecular Weight
527.08
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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