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NCT-503

Product Specifications

CAS Number

1916571-90-8

Target

TAM Receptor, FLT, Dehydrogenase

Related Pathways

Metabolism, Tyrosine Kinase/Adaptors, Angiogenesis

Purity

0.9984

Bioactivity

NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50=2.5 μM) with no activity against other dehydrogenases. NCT-503 has antitumor activity and inhibits the growth of PHGDH-dependent tumors.

Smiles

Cc1cc(C)nc(NC(=S)N2CCN(Cc3ccc(cc3)C(F)(F)F)CC2)c1

Molecular Formula

C20H23F3N4S

Molecular Weight

408.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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