NCT-503
Product Specifications
CAS Number
1916571-90-8
Target
TAM Receptor, FLT, Dehydrogenase
Related Pathways
Metabolism, Tyrosine Kinase/Adaptors, Angiogenesis
Purity
0.9984
Bioactivity
NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50=2.5 μM) with no activity against other dehydrogenases. NCT-503 has antitumor activity and inhibits the growth of PHGDH-dependent tumors.
Smiles
Cc1cc(C)nc(NC(=S)N2CCN(Cc3ccc(cc3)C(F)(F)F)CC2)c1
Molecular Formula
C20H23F3N4S
Molecular Weight
408.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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